Abstract
Microalgae feature the ability to develop in different ecosystems, consequently because they are photosynthetic microorganisms with a simple structure. Recently, the interest production of microalgae-based products has increased, due to the integrity of these natural microorganisms in the production of fatty acids, lipids, carbohydrates, pigments, proteins, vitamins, antioxidants, enzymes, and bioactive molecules. It is crucial to study cultivation systems, species, and environmental factors, as they may have strong mastery over the cultivation of microalgae. Microalgae require cheap substrates, such as sunlight, temperature, and carbon dioxide, being used as affordable and effective biocatalysts to obtain products with high added value and commercial applicability (nutraceuticals, pharmaceuticals, biofuels, cosmetics, and functional foods, among others). Therefore, this chapter reports on the mechanisms of formation, production, and application of these components from microalgae (chemicals, enzymes, and bioactive molecules), in addition to providing a description of microalgae-based products, improving the application of microalgal biomass in several segments.
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References
Afreen S, Shamsi TN, Baig MA et al (2017) Um romance multicopper oxidase (lacase) de cianobactérias: purificação, caracterização com potencial na descoloração de corante antraquinônico. PLoS One 12:1–20. https://doi.org/10.1371/journal.pone.0175144
Aguilar JGS, Sato HH (2018) Microbial proteases: production and application in obtaining protein hydrolysates. Food Res Int 103:253–262. https://doi.org/10.1016/j.foodres.2017.10.044
Almeida JM, Alnoch RC, Souza EM et al (2020) Metagenomics: is it a powerful tool to obtain lipases for application in biocatalysis? BBA-Proteins Proteom 1868(2):140320. https://doi.org/10.1016/j.bbapap.2019.140320
Apt KE, Behrens PW (1999) Commercial developments in microalgal biotechnology. J Phycol 35(2):215–226. https://doi.org/10.1046/j.1529-8817.1999.3520215.x
Azzopardi E, Lloyd C, Teixeira SR et al (2016) Clinical applications of amylase: novel perspectives. Surgery 160(1):26–37. https://doi.org/10.1016/j.surg.2016.01.005
Baldev E, MubarakAli D, Ilavarasi A et al (2013) Degradation of synthetic dye, rhodamine B to environmentally non-toxic products using microalgae. Colloids Surf B Biointerfaces 105:207–214. https://doi.org/10.1016/j.colsurfb.2013.01.008
Bekirogullari M, Fragkopoulos IS, Pittman JK et al (2017) Production of lipid-based fuels and chemicals from microalgae: an integrated experimental and model-based optimization study. Algal Res 23:78–87. https://doi.org/10.1016/j.algal.2016.12.015
Bellou S, Baeshen MN, Elazzazy AM et al (2014) Microalgal lipids biochemistry and biotechnological perspectives. Biotechnol Adv 32(8):1476–1493. https://doi.org/10.1016/j.biotechadv.2014.10.003
Bentahar J, Doyen A, Beaulieu L et al (2018) Investigation of β-galactosidase production by microalga Tetradesmus obliquus in determined growth conditions. J Appl Phycol 31:301–308. https://doi.org/10.1007/s10811-018-1550-y
Bhalamurugan GL, Valerie O, Mark L et al (2018) Valuable bioproducts obtained from microalgal biomass and their commercial applications: a review. Environ Eng Res 23(3):229–241. https://doi.org/10.4491/eer.2017.220
Bhattacharya M, Goswami S (2020) Microalgae-a green multi-product biorefinery for future industrial prospects. Biocatal Agric Biotechnol 101580. https://doi.org/10.1016/j.bcab.2020.101580
Borowitzka MA (2013) High-value products from microalgae-their development and commercialisation. J Appl Phycol 25(3):743–756. https://doi.org/10.1007/s10811-013-9983-9
Brasil BSAF, Siqueira FG, Salum TFC et al (2017) Microalgae and cyanobacteria as enzyme biofactories. Algal Res 25:76–89. https://doi.org/10.1016/j.algal.2017.04.035
Caporgno MP, Mathys A (2018) Trends in microalgae incorporation into innovative food products with potential health benefits. Front Nutr 5:58. https://doi.org/10.3389/fnut.2018.00058
Chen J, Wang Y, Benemann JR et al (2016) Microalgal industry in China: challenges and prospects. J Appl Phycol 28(2):715–725. https://doi.org/10.1007/s10811-015-0720-4
Chew KW, Yap JY, Show PL et al (2017) Microalgae biorefinery: high value products perspectives. Bioresour Technol 229:53–62. https://doi.org/10.1016/j.biortech.2017.01.006
Chisti Y (2007) Biodiesel from microalgae. Biotechnol Adv 25(3):294–306. https://doi.org/10.1016/j.biotechadv.2007.02.001
Chu WL, Phang SM, Miyakawa K et al (2002) Influence of irradiance and inoculum density on the pigmentation of Spirulina platensis. Asia Pac J Mol Biol Biotechnol 10(2):109–117
Cripwell R A, Van Zyl WH, Viljoen-Bloom M (2020) Fungal biotechnology: fungal amylases and their applications. Elsevier. doi: https://doi.org/10.1016/b978-0-12-809633-8.21082-0
Davies CM, Apte SC, Peterson SM et al (1994) Plant and algal interference in bacterial β-D-galactosidase and β-D-glucuronidase assays. Appl Environ Microbiol 60:3959–3964. https://doi.org/10.1128/AEM.60.11.3959-3964.1994
Demir BS, Teukel SS (2010) Purification and characterization of lipase from Spirulina platensis. J Mol Catal B Enzym 64:123–128. https://doi.org/10.1016/j.molcatb.2009.09.011
Dey PM, Kauss H (1981) α-Galactosidase of Poterioochromonas malhamensis. Phytochemistry 20:45–48. https://doi.org/10.1016/0031-9422(81)85216-8
Ejike CE, Collins SA, Balasuriya N et al (2017) Prospects of microalgae proteins in producing peptide-based functional foods for promoting cardiovascular health. Trends Food Sci Tech 59:30–36. https://doi.org/10.1016/j.tifs.2016.10.026
Ellatif SA, El-Sheekh MM, Senousy HH (2020) Role of microalgal ligninolytic enzymes in industrial dye decolorization. Int J Phytoremediation:1–12. https://doi.org/10.1080/15226514.2020.1789842
Enamala MK, Enamala S, Chavali M et al (2018) Production of biofuels from microalgae-a review on cultivation, harvesting, lipid extraction, and numerous applications of microalgae. Renew Sust Energ Rev 94:49–68. https://doi.org/10.1016/j.rser.2018.05.012
Eriksen NT (2008) The technology of microalgal culturing. Biotechnol Lett 30(9):1525–1536. https://doi.org/10.1007/s10529-008-9740-3
Erpel F, Restovic F, Arce-Johnson P (2016) Development of phytase-expressing Chlamydomonas reinhardtii for monogastric animal nutrition. BMC Biotechnol 16(1):1–7. https://doi.org/10.1186/s12896-016-0258-9
Fabregas J, Herrero C (1990) Vitamin content of four marine microalgae. Potential use as source of vitamins in nutrition. J Ind Microbiol 5(4):259–263. https://doi.org/10.1007/BF01569683
Fagundes MB, Vendruscolo RG, Wagner R (2020) In: Jacob-Lopes E, Maroneze MM, Queiroz MI, Zepka LQ (eds) Sterols from microalgae. Handbook of microalgae-based processes and products. Academic Press. p 573–596. doi:https://doi.org/10.1016/b978-0-12-818536-0.00021-x.
Fernandes BD, Mota A, Teixeira JA et al (2015) Continuous cultivation of photosynthetic microorganisms: approaches, applications and future trends. Biotechnol Adv 33(6):1228–1245. https://doi.org/10.1016/j.biotechadv.2015.03.004
Geada P, Vasconcelos V, Vicente A et al (2017) In: Rastogi RP, Madamwar D, Pandey A (eds) Microalgal biomass cultivation. Algal green chemistry. Elsevier. p 257-284. doi: 10.1016/B978-0-444-63784-0.00013-8.
Geada P, Rodrigues R, Loureiro L et al (2018) Electrotechnologies applied to microalgal biotechnology-applications, techniques and future trends. Renew Sust Energ Rev 94:656–668. https://doi.org/10.1016/j.rser.2018.06.059
Gimpel JA, HenrÃquez V, Mayfield SP (2015) In the metabolic engineering of eukaryotic microalgae: potential and challenges come with great diversity. Front Microbiol 6:1376. https://doi.org/10.3389/fmicb.2015.01376
Giordano M, Wang Q (2018) In: Vaz S Jr (ed) Microalgae for industrial purposes, Biomass and green chemistry. Springer, Cham, pp 133–167. https://doi.org/10.1007/978-3-319-66736-2_6
Girard J-M, Roy M-L, Hafsa MB et al (2014) Mixotrophic cultivation of green microalgae Scenedesmus obliquus on cheese whey permeate for biodiesel production. Algal Res 5:241–248. https://doi.org/10.1016/j.algal.2014.03.002
Godet S, Herault J, Pencreach G et al (2012) Isolation and analysis of a gene from the marine microalga Isochrysis galbana that encodes a lipase-like protein. J Appl Phycol 24:1547–1553. https://doi.org/10.1007/s10811-012-9815-3
Graziani G, Schiavo S, Nicolai MA et al (2013) Microalgae as human food: chemical and nutritional characteristics of the thermo-acidophilic microalga Galdieria sulphuraria. Food Funct 4(1):144–152. https://doi.org/10.1039/C2FO30198A
Handa V, Sharma D, Kaur A et al (2020) Biotechnological applications of microbial phytase and phytic acid in food and feed industries. Biocatal Agri Biotechnol 25:101600. https://doi.org/10.1016/j.bcab.2020.101600
Hess SK, Lepetit B, Kroth PG et al (2018) Production of chemicals from microalgae lipids–status and perspectives. Eur J Lipid Sci Tech 120(1):1700152. https://doi.org/10.1002/ejlt.201700152
Ho SH, Huang SW, Chen CY et al (2013) Bioethanol production using carbohydrate-rich microalgae biomass as feedstock. Bioresour Technol 135:191–198. https://doi.org/10.1016/j.biortech.2012.10.015
Hong JW, Jo SW, Yoon HS (2015) Research and development for algae-based technologies in Korea: a review of algae biofuel production. Photosynth Res 123(3):297–303. https://doi.org/10.1007/s11120-014-9974-y
Hubert F, Poisson L, Loiseau C et al (2017) Lipids and lipolytic enzymes of the microalga Isochrysis galbana. Oilseeds fats crop lipids 24: D407. Doi: 10.1051 / ocl / 2017023
Husain Q (2010) β galactosidases and their potential applications: a review. Crit Rev Biotechnol 30:41–62. https://doi.org/10.3109/07388550903330497
Jacob-Lopes E, Maroneze MM, Deprá MC et al (2019) Bioactive food compounds from microalgae: an innovative framework on industrial biorefineries. Curr Opin Food Sci 25:1–7. https://doi.org/10.1016/j.cofs.2018.12.003
Japar AS, Takriff MS, Yasin NHM (2017) Harvesting microalgal biomass and lipid extraction for potential biofuel production: a review. J Environ 5(1):555–563. https://doi.org/10.1016/j.jece.2016.12.016
Jha D, Jain V, Sharma B et al (2017) Microalgae based pharmaceuticals and nutraceuticals: an emerging field with immense market potential. Chembioeng Rev 4(4):257–272. https://doi.org/10.1002/cben.201600023
Joshi S, Kumari R, Upasani VN (2018) Applications of algae in cosmetics: an overview. Int J Innov Res Sci Eng Technol 7(2):1269. https://doi.org/10.15680/IJIRSET.2018.0702038
Junior WGM, Gorgich M, Corrêa PS et al (2020) Microalgae for biotechnological applications: cultivation, harvesting and biomass processing. Aquac 735562. https://doi.org/10.1016/j.aquaculture.2020.735562
Klanbut K, Peerapornpisarn Y, Khanongnuch C et al (2002) Phytase from some strains of thermophilic blue-green algae. J Phycol S2:57–60
Koller M, Salerno A, Tuffner P et al (2012) Characteristics and potential of micro algal cultivation strategies: a review. J Clean Prod 37:377–388. https://doi.org/10.1016/j.jclepro.2012.07.044
Koller M, Muhr A, Braunegg G (2014) Microalgae as versatile cellular factories for valued products. Algal Res 6:52–63. https://doi.org/10.1016/j.algal.2014.09.002
Kombrink E, Weober G (1980) Identification and subcellular localization of starch-metabolizing enzymes in the green alga Dunaliella marina. Planta 149:130–137. https://doi.org/10.1007/BF00380873
Lafarga T, Fernández-Sevilla JM, González-López C et al (2020) Spirulina for the food and functional food industries. Food Res Int 109356. https://doi.org/10.1016/j.foodres.2020.109356
Lee YK (1997) Commercial production of microalgae in the Asia-Pacific rim. J Appl Phycol 9(5):403–411. https://doi.org/10.1023/A:1007900423275
Levasseur W, Perré P, Pozzobon V (2020) A review of high value-added molecules production by microalgae in light of the classification. Biotechnol Adv 107545. https://doi.org/10.1016/j.biotechadv.2020.107545
Levi C, Gibbs M (1984) Starch degradation in synchronously grown Chlamydomonas reinhardtii and characterization of the amylase. Plant Physiol 74:459–463. https://doi.org/10.1104/pp.74.3.459
Li X, Li S, Liang X et al (2020) Applications of oxidases in modification of food molecules and colloidal systems: laccase, peroxidase and tyrosinase. Trends Food Sci Tech 103:78–93. https://doi.org/10.1016/j.tifs.2020.06.014
Lockau W, Massalsky B, Dirmeier A (1988) Purification and partial characterization of a calcium-stimulated protease from the cyanobacterium, Anabaena variabilis. Eur J Biochem 172:433–438. https://doi.org/10.1111/j.1432-1033.1988.tb13906.x
Maeda Y, Yoshino T, Matsunaga T et al (2018) Marine microalgae for production of biofuels and chemicals. Curr Opin Biotech 50:111–120. https://doi.org/10.1016/j.copbio.2017.11.018
Manoj BS, Sushma CM, Karosiya A (2018) Western Ghats terrestrial microalgae serve as a source of amylase and antioxidants enzymes. J Pharmacogn Phytochem 7:1555–1560
Markou G, Nerantzis E (2013) Microalgae for high-value compounds and biofuels production: a review with focus on cultivation under stress conditions. Biotechnol Adv 31(8):1532–1542. https://doi.org/10.1016/j.biotechadv.2013.07.011
Markou G, Angelidaki I, Georgakakis D (2012) Microalgal carbohydrates: an overview of the factors influencing carbohydrates production, and of main bioconversion technologies for production of biofuels. Appl Microbiol Biot 96(3):631–645. https://doi.org/10.1007/s00253-012-4398-0
Mata TM, Martins AA, Caetano NS (2010) Microalgae for biodiesel production and other applications: a review. Renew Sust Energ Rev 14(1):217–232. https://doi.org/10.1016/j.rser.2009.07.020
Matos ÂP (2017) The impact of microalgae in food science and technology. J Am Oil Chem Soc 94(11):1333–1350. https://doi.org/10.1007/s11746-017-3050-7
Medina JDC, Woiciechowski AL, Guimarães LRC et al (2016) In: Pandey a, Negi S, Soccol CR (eds) peroxidases. Current developments in biotechnology and bioengineering: production, isolation and purification of industrial products. Elsevier, p. 217-232. doi: https://doi.org/10.1016/B978-0-444-63662-1.00010-5
Mehta D, Satyanarayana T (2016) Bacterial and archaeal α-amylases: diversity and amelioration of the desirable characteristics for industrial applications. Front Microbiol 7:1129. https://doi.org/10.3389/fmicb.2016.01129
Mobin S, Alam F (2017) Some promising microalgal species for commercial applications: a review. Energy Procedia 110:510–517. https://doi.org/10.1016/j.egypro.2017.03.177
Mohanan N, Satyanarayana T (2019) Amylases. In: Schmidt TM (ed) Encyclopedia of microbiology. Fourth, p. 107-126
Moradi S, Ziaei R, Foshati S et al (2019) Effects of spirulina supplementation on obesity: a systematic review and meta-analysis of randomized clinical trials. Complement Ther Med 47:102211. https://doi.org/10.1016/j.ctim.2019.102211
de Morais WGJ, Gorgich M, Corrêa PS et al (2020) Microalgae for biotechnological applications: cultivation, harvesting and biomass processing. Aquac 735562. https://doi.org/10.1016/j.aquaculture.2020.735562
Murphy CD, Moore RM, White RL (2000) Peroxidases from marine microalgae. J Appl Phycol 12:507–513. https://doi.org/10.1023/A:1008154231462
Nanni B, Balestreri E, Dainese E et al (2001) Characterization of a specific Phycocyanin hydrolysing protease purified from Spirulina platensis. Microbiol Res 156:259–266. https://doi.org/10.1078/0944-5013-00110
Nascimento TC, Cazarin CBB, Maróstica JMR et al (2020a) Microalgae carotenoids intake: influence on cholesterol levels, lipid peroxidation and antioxidant enzymes. Food Res Int 128:108770. https://doi.org/10.1016/j.foodres.2019.108770
Nascimento TC, Nass PP, Fernandes AS et al (2020b) Exploratory data of the microalgae compounds for food purposes. Data Brief 29:105182. https://doi.org/10.1016/j.dib.2020.105182
Naumoff DG (2011) Hierarchical classification of glycoside hydrolases. Biochem Mosc 76:622–635. https://doi.org/10.1134/s0006297911060022
Niven GW (1995) The characterization of two aminopeptidase activities from the cyanobacterium Anabaena flosaquae. Biochim Biophys Acta Protein Struct Mol Enzymol 1253:193–198. https://doi.org/10.1016/0167-4838(95)00175-0
Nur MMA, Buma AG (2019) Opportunities and challenges of microalgal cultivation on wastewater, with special focus on palm oil mill effluent and the production of high value compounds. Waste Biomass Valorization 10(8):2079–2097. https://doi.org/10.1007/s12649-018-0256-3
Oesterhelt C, Vogelbein S, Shrestha RP et al (2008) The genome of the thermoacidophilic red microalga Galdieria sulphuraria encodes a small family of secreted class III peroxidases that might be involved in cell wall modification. Planta 227:353–362. https://doi.org/10.1007/s00425-007-0622-z
OlguÃn EJ (2012) Dual purpose microalgae-bacteria-based systems that treat wastewater and produce biodiesel and chemical products within a biorefinery. Biotechnol Adv 30(5):1031–1046. https://doi.org/10.1016/j.biotechadv.2012.05.001
Otto B, Schlosser D, Reisser W (2010) First description of a laccase-like enzyme in soil algae. Arch Microbiol 192:759–768. https://doi.org/10.1007/s00018-009-0169-1
Otto B, Beuchel C, Liers C et al (2015) Laccase-like enzyme activities from chlorophycean green algae with potential for bioconversion of phenolic pollutants. FEMS Microbiol Lett 362:1–8. https://doi.org/10.1093/femsle/fnv072
Overbaugh JM, Fall R (1982) Detection of glutathione peroxidases in some microalgae. FEMS Microbiol Lett 13:371–375. https://doi.org/10.1111/j.1574-6968.1982.tb08290.x
Overbaugh JM, Fall R (1985) Characterization of a selenium-independent glutathione peroxidase from Euglena gracilis. Plant Physiol 77:437–442. https://doi.org/10.1104/pp.77.2.437
Patias LD, Maroneze MM, Siqueira SF et al (2018) Single-cell protein as a source of biologically active ingredients for the formulation of Antiobesity foods. Alternative and Replacement Foods:317–353. https://doi.org/10.1016/b978-0-12-811446-9.00011-3
Patil K, Mahajan RT (2016) Enzymatic study of fresh water macro and micro algae isolated from Jalgaon, Maharashtra. Int J Pharm Bio Sci 7:207–215. https://doi.org/10.4172/2155-952X.C1.068
Patil KJ, Mahajan RT, Mahajan SR et al (2001) Enzyme profile of fresh water uncultured algae belonging to Bhusawal region, Maharashtra. J Chem biosphere 2(1): 33-28. Doi: https://doi.org/10.20546/ijcrbp.2016.301.013
Pignolet O, Jubeau S, Vaca-Garcia C et al (2013) Highly valuable microalgae: biochemical and topological aspects. J Ind Microbiol Biot 40(8):781–796. https://doi.org/10.1007/s10295-013-1281-7
Pragya N, Pandey KK, Sahoo PK (2013) A review on harvesting, oil extraction and biofuels production technologies from microalgae. Renew Sust Energ Rev 24:159–171. https://doi.org/10.1016/j.rser.2013.03.034
Rahman KM (2020) In: Alam MA, Jing-Liang X, Zhongming W (eds) Food and high value products from microalgae: market opportunities and challenges. Microalgae biotechnology for food, health and high value products. Springer, Singapore, . p 3-27. doi: 10.1007/978-981-15-0169-2_1
Raja R, Hemaiswarya S, Ganesan V et al (2016) Recent developments in therapeutic applications of cyanobacteria. Crit Rev Microbiol 42(3):394–405. https://doi.org/10.3109/1040841X.2014.957640
Raposo MFJ, de Morais RMSC, de Morais AMMB (2013a) Health applications of bioactive compounds from marine microalgae. Life Sci 93(15):479–486. https://doi.org/10.1016/j.lfs.2013.08.002
Raposo MFDJ, De Morais RMSC, Bernardo de Morais AMM (2013b) Bioactivity and applications of sulphated polysaccharides from marine microalgae. Mar Drugs 11(1):233–252. https://doi.org/10.3390/md11010233
Rizwan M, Mujtaba G, Memon SA et al (2018) Exploring the potential of microalgae for new biotechnology applications and beyond: a review. Renew Sust Energ Rev 92:394–404. https://doi.org/10.1016/j.rser.2018.04.034
Rocha CM, Genisheva Z, Ferreira-Santos P et al (2018) Electric field-based technologies for valorization of bioresources. Bioresour Technol 254:325–339. https://doi.org/10.1016/j.biortech.2018.01.068
Rodrigues DB, Menezes CR, Mercadante AZ et al (2015) Bioactive pigments from microalgae Phormidium autumnale. Food Res Int 77:273–279. https://doi.org/10.1016/j.foodres.2015.04.027
Savvidou MG, Sotiroudis TG, Kolisis FN (2016) Cell surface and cellular debris-associated heat-stable lipolytic enzyme activities of the marine alga Nannochloropsis oceanica. Biocatal Biotransformation 34:24–32. https://doi.org/10.1080/10242422.2016.1212843
Sharma KM, Kumar R, Panwar S et al (2017) Microbial alkaline proteases: optimization of production parameters and their properties. J Genet Eng Biotechnol 15(1):115–126. https://doi.org/10.1016/j.jgeb.2017.02.001
Sharma A, Ahluwalia O, Tripathi AD et al (2020) Phytases and their pharmaceutical applications: mini-review. Biocatal Agric Biotechnol 23:101439. https://doi.org/10.1016/j.bcab.2019.101439
da Silva Vaz B, Moreira JB, de Morais MG et al (2016) Microalgae as a new source of bioactive compounds in food supplements. Curr Opin Food Sci 7:73–77. https://doi.org/10.1016/j.cofs.2015.12.006
Silva PEC, Souza FASD, Barros RC et al (2017) Enhanced production of fibrinolytic protease from microalgae Chlorella vulgaris using glycerol and corn steep liquor as nutrient. Ann Microbiol Res 1: 9-19. Doi: 10.36959/958/564
Spier MR, Peron-schlosser B, Paludo LC et al (2020) Microalgae as enzymes biofactories. In: Jacob-Lopes E, Queiroz MI, Maroneze MM, Zepka LQ (eds) Handbook of microalgae-based processes and products. Academic, New York, pp 687–706. https://doi.org/10.1016/B978-0-12-818536-0.00025-7
Spolaore P, Joannis-Cassan C, Duran E et al (2006) Commercial applications of microalgae. J Biosci Bioeng 101(2):87–96. https://doi.org/10.1263/jbb.101.87
Strohmeier U, Gerdes C, Lockau W (1994) Proteolysis in heterocyst-forming cyanobacteria: characterization of a further enzyme with trypsin-like specificity, and of a prolyl endopeptidase from Anabaena variabilis. Z Naturforsch C J Biosci 49:70–78. https://doi.org/10.1515/znc-1994-1-212
Suwal S, Bentahar J, Marciniak A et al (2019) Evidence of the production of galactooligosaccharide from whey permeate by the microalgae Tetradesmus obliquus. Algal Res 39:101470. https://doi.org/10.1016/j.algal.2019.101470
Tang DYY, Khoo KS, Chew KW et al (2020) Potential utilization of bioproducts from microalgae for the quality enhancement of natural products. Bioresour Technol 304:122997. https://doi.org/10.1016/j.biortech.2020.122997
Um BH, Kim YS (2009) A chance for Korea to advance algal-biodiesel technology. J Ind Eng Chem 15(1):1–7. https://doi.org/10.1016/j.jiec.2008.08.002
Vidya CH, Kumar BS, Chinmayee CV et al (2020) Purification, characterization and specificity of a new GH family 35 galactosidase from Aspergillus awamori. Int J Biol Macromol 156:885–895. https://doi.org/10.1016/j.ijbiomac.2020.04.013
Vilchez C, Garbayo I, Lobato MV et al (1997) Microalgae-mediated chemicals production and wastes removal. Enzyme Microb Technol 20(8):562–572. https://doi.org/10.1016/S0141-0229(96)00208-6
Vonshak A (1997) Microalgal biotechnology: new development in production facilities and products. In 2: Asia-Pacific marine biotechnology conference and 3. Asia-Pacific conference on algal biotechnology, Phuket (Thailand)
Yada E, Nagata H, Noguchi Y et al (2005) An arginine specific protease from Spirulina platensis. Mar Biotechnol 7:474–480. https://doi.org/10.1007/s10126-004-4115-9
Yen HW, Hu IC, Chen CY et al (2013) Microalgae-based biorefinery-from biofuels to natural products. Bioresour Technol 135:166–174. https://doi.org/10.1016/j.biortech.2012.10.099
Yong SK, Lim BH, Saleh S et al (2016) Optimisation, purification and characterization of extracellular lipase from Botryococcus sudeticus (UTEX 2629). J Mol Catal B Enzym 126:99–105. https://doi.org/10.1016/j.molcatb.2016.02.004
Zanette CM, Mariano AB, Yukawa YS et al (2019) Microalgae mixotrophic cultivation for β-galactosidase production. J Appl Phycol 31:1597. https://doi.org/10.1007/s10811-018-1550-y
Zepka LQ, Jacob-Lopes E, Goldbeck R et al (2010) Nutritional evaluation of single-cell protein produced by Aphanothece microscopica Nägeli. Bioresour Technol 101(18):7107–7111. https://doi.org/10.1016/j.biortech.2010.04.001
Zepka LQ, Jacob-Lopes E, Roca M (2019) Catabolism and bioactive properties of chlorophylls. Curr Opin Food Sci 26:94–100. https://doi.org/10.1016/j.cofs.2019.04.004
Zhao R, Zhao R, Tu Y et al (2018) A novel α-galactosidase from the thermophilic probiotic Bacillus coagulans with remarkable protease-resistance and high hydrolytic activity. PLoS One 13:e0197067. https://doi.org/10.1371/journal.pone.0197067
Zhu LD, Hiltunen E (2016) Application of livestock waste compost to cultivate microalgae for bioproducts production: a feasible framework. Renew Sust Energ Rev 54:1285–1290. https://doi.org/10.1016/j.rser.2015.10.093
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Lasta, P., da Silva, P.A., Caetano, P.A., Pinheiro, P.N., Zepka, L.Q., Jacob-Lopes, E. (2022). Microalgae Application in Chemicals, Enzymes, and Bioactive Molecules. In: Inamuddin, Ahamed, M.I., Prasad, R. (eds) Application of Microbes in Environmental and Microbial Biotechnology. Environmental and Microbial Biotechnology. Springer, Singapore. https://doi.org/10.1007/978-981-16-2225-0_14
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