Moringa (Moringa oleifera Lam.) polysaccharides: Extraction, characterization, bioactivities, and industrial application

Kanika Sharma; Manoj Kumar; Roji Waghmare; Rajat Suhag; Om Prakash Gupta; José M Lorenzo; Suraj Prakash; Radha; Nadeem Rais; Vellaikumar Sampathrajan; Chandan Thappa; T Anitha; Ali A S Sayed; Basel A Abdel-Wahab; Marisennayya Senapathy; R Pandiselvam; Abhijit Dey; Sangram Dhumal; Ryszard Amarowicz; John F Kennedy

doi:10.1016/j.ijbiomac.2022.04.047

Moringa (Moringa oleifera Lam.) polysaccharides: Extraction, characterization, bioactivities, and industrial application

Int J Biol Macromol. 2022 Jun 1;209(Pt A):763-778. doi: 10.1016/j.ijbiomac.2022.04.047. Epub 2022 Apr 11.

Authors

Kanika Sharma¹, Manoj Kumar², Roji Waghmare³, Rajat Suhag⁴, Om Prakash Gupta⁵, José M Lorenzo⁶, Suraj Prakash⁷, Radha⁷, Nadeem Rais⁸, Vellaikumar Sampathrajan⁹, Chandan Thappa¹⁰, T Anitha¹¹, Ali A S Sayed¹², Basel A Abdel-Wahab¹³, Marisennayya Senapathy¹⁴, R Pandiselvam¹⁵, Abhijit Dey¹⁶, Sangram Dhumal¹⁷, Ryszard Amarowicz¹⁸, John F Kennedy¹⁹

Affiliations

¹ Chemical and Biochemical Processing Division, ICAR - Central Institute for Research on Cotton Technology, Mumbai 400019, India.
² Chemical and Biochemical Processing Division, ICAR - Central Institute for Research on Cotton Technology, Mumbai 400019, India. Electronic address: manoj.kumar13@icar.gov.in.
³ College of Food Technology, Dr. Punjabrao Deshmukh Krishi Vidyapeeth, Yavatmal 445001, Maharashtra, India.
⁴ National Institute of Food Technology Entrepreneurship and Management, Sonipat 131028, Haryana, India.
⁵ ICAR - Indian Institute of Wheat and Barley Research, Karnal 132001, Haryana, India.
⁶ Centro Tecnológico de la Carne de Galicia, rúa Galicia n 4, Parque Tecnológico de Galicia, San Cibrao das Viñas, 32900 Ourense, Spain; Área de Tecnología de los Alimentos, Facultad de Ciencias de Ourense, Universidad de Vigo, 32004 Ourense, Spain. Electronic address: jmlorenzo@ceteca.net.
⁷ School of Biological and Environmental Sciences, Shoolini University of Biotechnology and Management Sciences, Solan 173229, India.
⁸ Department of Pharmacy, Bhagwant University, Ajmer, Rajasthan 305004, India.
⁹ Agricultural College and Research Institute, Tamil Nadu Agricultural University, Madurai 625104, India.
¹⁰ Division of Biochemistry, Faculty of Basic Sciences, Sher-e-Kashmir University of Agricultural Sciences and Technology, Jammu 180009, India.
¹¹ Department of Postharvest Technology, Horticultural College and Research Institute, Periyakulam, 625604, India.
¹² Botany Department, Faculty of Agriculture, Fayoum University, Fayoum, 63514, Egypt; Division of Plant Physiology, ICAR - Indian Agricultural Research Institute, New Delhi, 110012, India.
¹³ Department of Medical Pharmacology, College of Medicine, Assiut University, Assiut 7111, Egypt; Department of Pharmacology, College of Pharmacy, Najran University, Najran, Saudi Arabia.
¹⁴ Department of Rural Development and Agricultural Extension, College of Agriculture, Wolaita Sodo University, Wolaita Sodo, Ethiopia.
¹⁵ Division of Physiology, Biochemistry and Post-Harvest Technology, ICAR - Central Plantation Crops Research Institute (CPCRI), Kasaragod 671 124, Kerala, India.
¹⁶ Department of Life Sciences, Presidency University, 86/1 College Street, Kolkata 700073, West Bengal, India.
¹⁷ Division of Horticulture, RCSM College of Agriculture, Kolhapur 416004, India. Electronic address: sangram1326@hotmail.com.
¹⁸ Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn, Poland.
¹⁹ Chembiotech Laboratories, Advanced Science and Technology Institute, Kyrewood House, Tenbury Wells, Worcs, WR15 8FF, UK.

PMID: 35421412
DOI: 10.1016/j.ijbiomac.2022.04.047

Abstract

Owing to numerous biological activities of different parts of Moringa oleifera Lam., various studies have been carried out to isolate and explore the activities of its various bioactive compounds including polysaccharides. Polysaccharides of M. oleifera have been reported to possess a variety of biofunctionalities including antihyperlipidemic, anti-diabetic, immunomodulatory, antihypertensive and gastrointestinal protection. In addition to bioactive polysaccharides, the gum exudated by stem of this plant is of commercial importance with wide range of applications in pharmaceutical industries. Various extraction and purification methods as well as combination of methods have been used to isolate and purify moringa polysaccharides. Studies suggest that extraction methods influence the structure of polysaccharides and thus their biological activity. This review summarizes all the available literature to provide updated information related to extraction, purification, modification, structural characterization, bioactivities and potential applications of moringa polysaccharides. This review will provide novel insights for future research and applications of moringa polysaccharides.

Keywords: Antioxidant; Bioactivities; Diseases; Extraction; Gut health; Polysaccharides; moringa.

Publication types

Review

MeSH terms

Antioxidants / chemistry
Moringa oleifera* / chemistry
Moringa*
Plant Extracts / chemistry
Plant Leaves / chemistry
Polysaccharides / analysis
Polysaccharides / pharmacology

Substances

Antioxidants
Plant Extracts
Polysaccharides